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Search Results for " interleukin 23 receptor "

Targets Recommended: IRAK CDK Haspin Kinase

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T14367	AZ1495	IRAK; CDK; Haspin Kinase	Cell Cycle/Checkpoint; Immunology/Inflammation; NF-κB
	AZ1495 是一种口服有活性的白介素-1受体相关激酶 4(IRAK4)抑制剂，能够作用于 IRAK4 (IC50:5 nM)和 IRAK1 (IC50:23 nM)。可用于研究突变型 MYD88L265P 弥漫性 B 细胞淋巴瘤 (DLBCL) 。

化合物

AZ1495

Cat.No: T14367

Synonym:

Target: IRAK, CDK, Haspin Kinase

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05274	IL-23R Protein, Human, Recombinant (His) interleukin 23 receptor	Human	HEK293 Cells
	IL-23R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.3 kDa and the accession number is AAM44229.1.
TMPY-00155	IL-23R Protein, Rat, Recombinant (His) interleukin 23 receptor	Rat	HEK293 Cells
	IL-23R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is F1LX96.
TMPY-03281	IL-23R Protein, Human, Recombinant (hFc) interleukin 23 receptor	Human	HEK293 Cells
	IL-23R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is AAM44229.1.
TMPY-03008	IL-23R Protein, Cynomolgus, Rhesus, Recombinant (hFc) interleukin 23 receptor	Cynomolgus,Rhesus	HEK293 Cells
	IL-23R Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.9 kDa and the accession number is F6XR82.
TMPJ-01219	IL-23R Protein, Mouse, Recombinant (hFc) Il23r,IL-23R,interleukin 23	Mouse	HEK293 Cells
	Interleukin 23 receptor (IL23R), a heterodimer of the IL12 receptor β1 (IL12Rβ1) and IL12Rβ2, is a type I cytokine receptor for IL23. IL23R is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, an...
TMPY-03245	IL-23R Protein, Rat, Recombinant (hFc) interleukin 23 receptor	Rat	HEK293 Cells
	IL-23R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 69.4 kDa and the accession number is F1LX96.
TMPJ-00351	IL-23R Protein, Human, Recombinant (aa 24-353, hFc) IL-23 receptor,IL23R,Interleu...	Human	HEK293 Cells
	Interleukin 23 receptor (IL23R) is a type I cytokine receptor for IL23. IL23 receptor complex is comprised of two subunits, the IL12Rβ1 subunit, which is shared with several cytokines, and a subunit that is unique to IL-23. IL23, after binding to IL23R, activates memory T cells and mediates pro-inflammatory activities in part by the production of IL17 through activation of TH17 lymphocytes. IL23R is expressed on T cells, NK cells, dendritic cells, and macrophages. In fact, polymorphisms of the I...
TMPK-01094	IL-23R Protein, Mouse, Recombinant (His) IL-23 receptor,Il23r,IBD17,IL-	Mouse	HEK293 Cells
	IL-23R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 41.48 kDa and the accession number is Q8K4B4.
TMPH-00779	IL-23 P19/IL23A Protein, Guinea Pig, Recombinant (His & Myc)	Guinea pig	E. coli
	Associates with IL12B to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible fo...
TMPK-01378	IL-12B Protein, Cynomolgus, Recombinant (His) CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS	Cynomolgus	HEK293 Cells
	Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi...
TMPJ-00047	IL-31 Protein, Human, Recombinant IL-31,Interleukin-31,白介素,白细胞介素,IL31	Human	E. coli
	Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes a 164 amino acid precursor that contains a 23 amino acid signal peptide and a 141 amino acid mature protein. Human and mouse IL-31 share 24% sequence identity in the mature region. IL-31 is mainly associated with activated T cells and is preferentially expressed by type 2 helper...